Ben G Small Development of a PBPK paediatric cancer population model
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Brian Cicali PBPK-based exposure bracketing of subcutaneous levonorgestrel for evaluating drug-drug interactions
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Shihao Hu PBPK Modeling to Predict mAb Pharmacokinetics from in vitro Biophysical Antibody Properties
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Expansion of LeiCNS-PK3.0 for the prediction of drug pharmacokinetic (PK) profile in brain tumors
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Mohammed Saleh A translational modeling approach to predict the impact of healthy aging on brain extracellular and intracellular PK profiles
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Opioids distribution in human CNS might be altered due to pain-related increase of BBB permeability
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Oleg Demin Jr PBPK modeling of T cell distribution in cancer patients
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Meta-Assessment of Metformin Absorption and Disposition Pharmacokinetics in Nine Species
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Shen Cheng A physiological-based Pharmacokinetic (PBPK) Model embedded with a Target Mediated Drug Disposition (TMDD) mechanism can characterize S-warfarin pharmacokinetic (PK) profiles in subjects with various CYP2C9 genotypes under different co-treatments
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Jin Dong Bilirubin as Endogenous Biomarkers for Hepatic OATP1B Inhibition in Healthy Volunteers and Chronic Kidney Disease Patients: A PBPK Modeling & Simulation Analysis
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Physiologically Based Pharmacokinetic Modeling of a Novel HER2-Targeted Antibody-Drug Conjugate, Trastuzumab Deruxtecan for Assessment of Pharmacokinetic Drug-Drug Interaction
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Chandrali Bhattacharya Translational Population-Pharmacokinetic & Physiologically-Based Pharmacokinetic Modeling Approach to Predict the Disposition of Bupropion and S, S-Hydroxybupropion in Human Brain.
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Dinesh Bharadwaj Bedathuru A physiologically-based ocular PKPD platform model for translational research and drug development
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PBPK/RO modeling of anti-PDL1 antibodies
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Julia Macente Model-informed precision dosing of levetiracetam in pediatrics population
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Aline Barth A Physiologically Based Pharmacokinetic Model for the Evaluation of Gepotidacin Drug-Drug Interactions
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A Physiologically-Based Pharmacokinetic (PBPK) Model to Evaluate Anti–PD-1 Blocking Antibody Engagement Dynamics in Tumor
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JAYDEEP SINHA Application of Physiologically-Based Pharmacokinetic Modeling to Estimate the Effect of Enzyme Inducing Anti-Epileptic Drugs on the Pharmacokinetics of Levetiracetam in Children
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Development of an Etonogestrel disposition model using PK-Sim for application to other dosage forms
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Physiologically-based pharmacokinetic modeling of ruxolitinib and posaconazole to predict the clinically relevant CYP3A4-mediated drug-drug interaction
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